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DNA
Immune Conditions
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VIZSLA INFLAMMATORY POLYMYOPATHY (VIP)

Vip is a myositis found specifically in the Vizsla breed, typical onset is usually is around 9 months to two years of age but it can affect dogs of any age and from any country/lineage.

Symptoms include-dribbling, difficulty swallowing, muscle wastage around the skulls inability to open the mouth correctly.

To date the exact cause has not been proven, levels of high inbreeding seem to play a role in some cases but some of the affected dogs are bred with very low COIs.

 At this time there is no test or pre breeding screening available but it is believed to be an autoimmune disorder due its response to treatment.

Research is being carried out in the hope that a pre breeding test can be found .

A database of pedigrees of affected dogs can be viewed here 

 

Masticatory Myositis  (MMM)

A type of Myositis that affects the Masticatory muscles causing difficulty chewing and pain.

It can be diagnosed using a specific antibody test.

 

 

Myasthenia Gravis

is an illness which causes generalised muscle weakness that can be exacerbated by exercise it can be diagnosed using a blood test.

 

 

IBD (Inflammatory Bowel Disease)

An illness that affects the inflammatory cells to the intestine, symptoms include Chronic vomiting, diarrhoea and weight loss.

 

 

Polyarthritis

is an immune-mediated inflammatory disease of joints. symptoms include fever, stiffness of gait, lameness, joint swelling and pain.

 

 

IMHA (Immune Mediated Haemolytic Anaemia)

An illness where the defective immune system attacks and destroys its own red blood cells causing Anaemia and other complications.

 

IMT (Immune Mediated Thrombocytopenia) 

An illness where the defective immune system attacks and destroys the platelets. Damaging clotting mechanisms and causing bleeding.

 

Sebaceous Adenitis

An inflammatory disease process directed against the sebaceous glands, resulting in the productions of scaly lesions affecting trunk, head and ears particularly.

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Pemphigus

An illness where the defective immune system targets cells between the skin layers or in mucous membranes causing Ulceration, crusting and pustules.

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Addison’s Disease

(primary) is caused by an autoimmune destruction of the adrenal glands resulting in the progressive loss of production of adrenal hormones. Clinical signs might include lethargy, vomiting/diarrhoea, anorexia, collapse. Diagnosis must be confirmed via ACTH stimulation test. 

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Symmetrical Lupoid Onychodystrophy (SLO)

results in destruction of the nail bed tissue which causes the nails to fall off and break. 

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